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Vitamin B-12 deficiency can cause weight gain
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Blunted or impeded therapeutic response to vitamin B12 may be due to such conditions as infection, uremia, drugs having bone marrow suppressant properties such as chloramphenicol, and concurrent iron or folic acid deficiency
Regular injections ensure a steady supply of B12
The choice of treatment should be individualised, considering the underlying cause, symptom severity, patient preference, and practical factors such as access to healthcare facilities for regular injections
Most research has focused on how this fragment may influence fat and energy metabolism in preclinical systems
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