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Integrated lactylome characterization reveals the molecular dynamics of protein regulation in gastrointestinal cancers

In HBP, fructose-6-phosphate (F-6-P) is converted to glucosamine-6-phosphate (Glucosamine-6-P) by glutamine:fructose-6-phosphate amidotransferase (GFAT), and glucosamine-6-P is converted to uridine 5-diphosphate N-acetylglucosamine (UDP-GlcNAc), which serves as the donor sugar nucleotide for the O-GlcNAcylation of lipids and proteins

doi:10.1177/1932296820911919

Tiew-Yik Ting and Wei-Jing Lee are co-first authors

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12 For example, Lambrechts et al