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The Grading of Recommendation, Assessment, Development, and Evaluation (GRADE) tool was used to assess the certainty of the evidence for the two primary biochemical outcomesserum vitamin B12 concentration increase and homocysteine reductionacross all included studies, and separately for randomised controlled trials (RCTs) and observational studies
Older adults, for instance, often have reduced stomach acid production, which can make it challenging to absorb B12 from food
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It is vital for dealing with vitamin B deficiency and thereby helpful in eliminating diseases like anemia
Correcting a low level takes that particular obstacle off the table
Alternatively, a translation (unofficial is sufficient) must be provided
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