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Blood glucose is elevated

The most commonly reported side effects in clinical trials include injection site reactions (redness, swelling, itching), fluid retention, joint pain, and in some cases transient glucose elevation

Weight loss achieved with the help of Semaglutide can also reduce fat mass, which can potentially help restore hormonal balance and improve metabolic function often caused by being overweight

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JAMA Network Another large observational study found that people with T2DM and obesity using semaglutide or tirzepatide had lower risk of dementia, stroke, and all-cause mortality compared to those on other glucoselowering agents

Weight-loss specialists explain that one-quarter to one-third of the weight lost is muscle, regardless of the tool: diet, bariatric surgery or medications