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The study "Liraglutide versus placebo as an adjunct to glucose-lowering therapy in patients with type 2 diabetes and moderate renal failure" (LIRA-RENAL) did not demonstrate a benefit of liraglutide in lowering eGFR, although the duration of the study (26 weeks) may have been insufficient to show an effect

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And in addition to causing your pancreas to release insulin, GLP-1 agonists also blocks a hormone that causes your liver to release sugar (glucagon)

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