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3.2.1 Impact of metformin on GDM in patients with polycystic ovary syndrome GDM is one of the most common pregnancy complications in patients with PCOS, with significant implications for both the mother and fetus

doi: 10.1038/s41598-020-79171-8 137 YangM.BoseS.LimS.SeoJ.ShinJ.LeeD.et al

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In humans, pre-proglucagon has 180 amino acids and is cleaved to yield proglucagon (158 amino acids), which lacks the N-terminal signalling sequence

Based on these principles, regardless of HbA 1c level or the presence of other glucose-lowering agents, all individuals with diabetes and established or subclinical CVD should be prescribed an agent with proven cardiovascular benefit from the GLP-1 RA class or SGLT2i class [5, 6]

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