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Cells were treated in triplicate with a serial dilution of IGF-1 LR3 for 4 hours
TB-500 is a synthetic peptide designed to mimic aspects of Thymosin Beta-4 activity, functioning through actin regulation, promoting cell migration and anti-inflammatory responses
Ann N Y Acad Sci 1470(1):1424 Winek K, Engel O, Koduah P, Heimesaat MM, Fischer A, Bereswill S et al (2016) Depletion of cultivatable gut microbiota by broad-spectrum antibiotic pretreatment worsens outcome after murine stroke
Studies have shown that it remains effective and works systemically this way (1, 19)
For example, inflammation is known to play a role in at least a subset of depressive 238 and psychotic disorders 239