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While there is some animal data and limited human research supporting its potential use case, its safety and efficacy profile is still not well-understood
In the knockout mice, there was no significant decrease in body weight or lipolysis, thus indicating the importance of the beta-adrenergic pathways in weight loss
In adipose models, reduced NNMT activity has been linked with smaller adipocyte size and diminished fat depots, suggesting a potential role for this inhibitor in fat mass modulation under research conditions
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Nicotinamide N-methyltransferase as a potential therapeutic target in neurodegenerative diseases
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