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Igarashi, I

When individuals exceed the recommended dosage, especially over an extended period, the likelihood of developing osteoporosis significantly rises

Unlike products that provide temporary plumping or instant cosmetic effects, GHK-Cu is generally viewed as a long-term skin-support ingredient

This was mainly driven by gastrointestinal related adverse events

ApoE2 astrocytes released more ApoE than ApoE4 astrocytes, though cellular ApoE levels were consistent across genotypes

These results suggest that HCA may promote the nuclear translocation of Nrf2, activate the transcription of antioxidant genes, and thereby activate the Nrf2/GPX4 pathway to exert its protective effects against ferroptosis