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If you have questions about administration or experience difficulties with the injection device, contact your diabetes care team or community pharmacist for guidance

For oral semaglutide (Rybelsus), the FDA prescribing information specifically notes increased thyroxine exposure when co-administered with levothyroxine

Maintain adequate fluid intake

Monitor blood sugar carefully pre and post operation

HbA1c lowering effect The results of the clinical trials demonstrated significantly greater reductions in A1C with liraglutide compared to exenatide, and both GLP-1 receptor agonists caused greater reductions than those observed with sitagliptin [7] Data regarding these four agents from published head-to-head studies suggest that Liraglutide may have the largest A1C lowering capability, followed by dulaglutide, exenatide once weekly and then exenatide twice daily ( Figure 5 ) [8-10] GLP-1 RA are associated with an A1c reduction of 0.5-1.5% which is greater than 0.5-1% from DPP4 inhibitors the in head to head Duration clinical trials [11]

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