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Research Interest Areas

After three steps of peroxisomal -oxidation, the medium-chain fatty acid product (4,8-dimethylnonanoic acid) is esterified to carnitine and transported out of the peroxisome for uptake by the mitochondria where it is further oxidized via the mitochondrial -oxidation pathway

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This enzymatic degradation is entirely dependent on the methylation cycle, which relies on methylcobalamin to produce the universal methyl donor, SAMe