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Dihexa might alleviate symptoms of neuroinflammation-related disorders by upregulating anti-inflammatory cytokines like IL-10

Obes Rev (2004) 5:14551

10.1016/S0300-9084(02)01375-5 Biochimie 75 HamadaS.KamadaM.FurumotoH.HiraoT.AonoT

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In a phase 2 study, comparing the results of the empagliflozin arm to the control arm showed a significant improvement in the electrophysiological studies and a significant decrease in the pain score and the mean serum levels of neuron-specific enolase and malondialdehyde in patients with DPN

Reduced Glutathione is in fact able to give up its hydrogen (H+), which acts as an acceptor of an electron (e-) coming from reactive oxygen molecules, that is, from free radicals