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It was originally developed to help manage type 2 diabetes and later received FDA approval at higher doses for chronic weight management in adults with obesity or overweight plus weight-related health conditions
That may explain why the Wegovy pill thats approved by the FDA is 25 mg while the Wegovy injection is only 2.4 mg
NICE guidance (CG189 and PH53) emphasises that sustainable weight loss is best achieved through a combination of dietary change, increased physical activity, and behavioural support rather than highly restrictive dieting alone
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Pharmacological inhibition of adipose triglyceride lipase corrects high-fat diet-induced insulin resistance and hepatosteatosis in mice
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