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It blocks the degradation of GLP-1 (7-37) by DPP-4 in the body, thereby prolonging the half-life of GLP-1 (7-37) in promoting insulin secretion and lowering blood sugar
In the intervention group, prandial insulin was discontinued and basal insulin reduced to 80% of the home dose or converted to glargine at 40% of the total daily dose for patients on premixed regimens
and (ii) to evaluate the ability of GSTP1 in protecting against AQ-QI- and DEAQ-QI-induced cytotoxicity
This reaction, when it occurs, typically reverses within two to four weeks of discontinuation