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Receptor Signalling Activates TGF-beta, VEGF, and FGF pathways - coordinating tissue regeneration, vascularisation, and the inflammatory resolution cascade

These diverse applications require extensive additional research to establish safety and efficacy profiles appropriate for clinical translation, but suggest GHK-Cu's therapeutic potential may extend substantially beyond current dermatological applications, potentially overlapping with emerging applications of other regenerative peptides including cerebrolysin for neurological applications and peptides targeting musculoskeletal regeneration

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References Jelovac, N., Sikiri, P., Rucman, R., Petek, M., Perovi, D., Konjevoda, P., Marovi, A., Seiwerth, S., Grabarevi, Z., Sumajstorci, J., Dodig, G., & Peri, J

Unlike muscles that enjoy rich vascular networks, tendons depend on a sparse collection of blood vessels that struggle to deliver the oxygen, nutrients, and growth factors needed for repair