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As these processes intensify, NAD stores are gradually depleted

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In particular, glutathione protects cells by neutralizing the effects of reactive hydroxyl free radicals and other oxygen-derived free radicals

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doi:10.1002/bit.260400806 Santos LO, Gonzales TA, Ubeda BT, Monte Alegre R (2007) Influence of culture conditions on glutathione production by Saccharomyces cerevisiae