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This knocked the inflammation down dramatically, and now Im hoping to maintain the results occasional maintenance treatments

How it works: GHRH receptor binding: Sermorelin binds pituitary somatotroph GHRH receptors, activating adenylyl cyclase and increasing intracellular cAMP to trigger synthesis and pulsatile release of endogenous GH IGF-1 upregulation: elevated GH drives hepatic IGF-1 production, which mediates the downstream anabolic effects including lean mass accretion, bone density support, and tissue remodeling Preserved feedback regulation: because sermorelin works through the hypothalamic-pituitary axis rather than bypassing it, natural somatostatin-mediated negative feedback remains intact, reducing the risk of GH excess seen with exogenous HGH Extracellular matrix support: preclinical models suggest GH axis stimulation may reduce inflammatory cytokine signaling and promote extracellular matrix remodeling, contributing to faster soft tissue recovery Administration: Subcutaneous injection (intramuscular also used) Typical dosing range: 200-500 mcg once daily, most protocols use 300 mcg nightly

Using the tumour microenvironment to improve therapy efficacy

Dehydration and electrolyte imbalance represent important safety concerns when diarrhoea occurs with either medication, and this risk may be heightened with concurrent use

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Month 1: the slow start that means everything Average weight loss: approximately 2 percent of body weight, with some trial participants losing up to 3.8 percent by week 4