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Concentrations of 20 mg/mL suit higher doses above 10 mg per week
Proc Natl Acad Sci USA 89(7):30603064 Isackson PJ, Huntsman MM, Murray KD, Gall CM (1991) BDNF mRNA expression is increased in adult rat forebrain after limbic seizures: temporal patterns of induction distinct from NGF
Trial averages at the highest dose (12 mg) reached around 24% body weight loss at 48 weeks, and around 28% at 68 weeks in the obesity plus knee osteoarthritis trial
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