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The second layer of the gut barrier is composed of a monolayer of intestinal epithelial cells and intercellular tight junction (TJ) proteins, with a scattered distribution of functionally specialized cells (e.g., Paneth, goblet, and enteroendocrine cells) (Ghosh et al., 2021)
Expect two to five days of increased nausea, possible changes in alcohol tolerance , constipation or diarrhea, and reduced energy after each increase
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