As one of the most thoroughly characterized GLP-1 receptor agonists, it has an exceptionally deep clinical and preclinical research record in metabolic science
Taken together, these data suggest CB0313.1 may mitigate energy metabolic dysfunction via reducing inflammatory tone and promoting mitochondrial metabolism in adipose tissue
Rosa AR, Singh N, Whitaker E, de Brito M, Lewis AM, Vieta E et al
The predominant active form of GLP-1 is 30amino acid GLP-1(736) amide (also known as GLP-1), which acts through a stimulatory G proteincoupled (Gs-coupled) GLP-1R
Cardiovascular outcome trials in patients with T2D have demonstrated the efficacy of GLP-1 RAs in reducing major adverse cardiovascular events, including cardiovascular death, MI and stroke, regardless of glycaemic control
What the Scientists Found When scientists dug deeper, they realized diabetes isnt just a matter of too much sugar. It sets off a cascade, like dominoes tipping into each other