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Ecological momentary assessment and cue-elicited drug craving as primary endpoints: study protocol for arandomized, double-blind, placebo-controlled clinical trial testing the efficacy of a GLP-1 receptor agonist in opioid use disorder
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Substantial weight loss can increase the risk of cholelithiasis Exclude organic causes of obesity (e.g., hypothyr oid ism) before prescribing Orlistat Patients should be advised to adhere to dietary guidelines
In the placebo-controlled analyses for change in HbA 1c and change in body weight, we conducted a post hoc sensitivity analysis excluding one trial with a short duration (12 weeks) [18] and one trial that recruited participants on background insulin therapy [19]
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