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A primary outcome event occurred in 12% (579 of 4,825) of patients in the semaglutide group (equivalent to 3.1 events per 100 personyears) and in 13.8% (668 of 4,825) of patients in the placebo group (equivalent to 3.7 events per 100 personyears)
It is easily broken down by digestive enzymes in the stomach, so it must be taken on an empty stomach for better absorption, and one cannot eat or drink water for 30 minutes after taking it
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It is not a complete safety profile or advice
In other words, tirzepatide may be associated with somewhat more hair shedding than some alternatives, but the most likely explanation is that tirzepatide produces more aggressive weight loss, which in turn triggers more pronounced telogen effluvium
Participants losing 50+ lbs often describe transformative improvements in mobility and reductions in chronic joint pain that had limited their activities for years
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