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Those who continued on the 12 mg dose to 104 weeks lost an average of 30.3% of their body weight (approximately 85.0 lbs / 38.6 kg) and importantly, weight loss continued without an obvious plateau, suggesting that durability over time may be achievable with continued treatment

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Because of their size and structure, many can work precisely at a cellular level, often mimicking natural messenger molecules like hormones or neurotransmitters

Early signs include swollen, tender, or bleeding gums, especially while brushing or flossing