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The trial used the efficacy estimand to measure the full glycaemic control potential of elecoglipron in patients who followed treatment as directed, providing the biological data needed to confirm optimal dosing for Phase III trials

Thomas A, Grgens C, Guddat S, et al

When taken with ibuprofen, they can heighten bleeding risk

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2030 h for metabolites, in Study 2) and the semaglutide dosing interval