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According to the generally accepted multiple-hit theory, oxidative stress and changes in antioxidant systems play an important role in MASLD progression as the starting point of hepatic and extrahepatic damage
Nonetheless, the exact mechanisms underlying the GLP-1 RA-associated HR acceleration are still unclear and these preliminary study results involving healthy male subjects cannot be over-generalized to a diabetic population using GLP-1 RAs
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J Biomed Nanotechnol
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