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T-tubule remodeling in cardiomyocytes TMAO disturbed myocardial excitation-contraction coupling by inducing Ca 2+ dysfunction (103)
Many studies have shown that the gut microbiota plays a crucial role in brain function and changes in the behavior of individuals and the formation of bacterial amyloids
These systems more closely recapitulate the heterogeneity and complexity of human metabolic processes 12,13,14
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Singh highlighted two 2025 studies: one found GLP-1 use was associated with a lower incidence of progression to advanced AMD, including neovascular AMD and geographic atrophy, while another reported an increased risk of neovascular AMD among GLP-1 users
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