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34 The trial had a total of 731 patients with a baseline mean A1C of 8.2% and a baseline total daily dose of insulin ranging from 56 to 62 units, depending on the treatment group
Receptor activation triggers a phospholipase C cascade, intracellular calcium mobilisation, and downstream stimulation of growth hormone secretion
It is also a substrate for sirtuins, a family of NAD+-dependent deacetylases that regulate metabolism, inflammation, and aging
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4: Hahn, A., Wolters, M
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