The result was validated using Western blot analysis, which showed the significantly lower expression level of PEDF after sevoflurane exposure (NC vs
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Chemokines such as CCL2, CCL18, and CXCL12 are instrumental in promoting either a pro-inflammatory M1 phenotype, which is associated with pathogen clearance and tissue damage, or an anti-inflammatory M2 phenotype, which is involved in tissue repair, fibrosis, and tumor progression (65)
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