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Higher gut permeability leads to influx of antigens, endotoxins, pathogens, and other proinflammatory substances from gut into the blood and lymphatic circulation, leading to systemic inflammation

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J Environ Biol 34:673676 Clay K, Leuchtmann A (1989) Infection of woodland grasses by fungal endophytes

Heidenreich PA, Bozkurt B, Aguilar D, Allen LA, Byun JJ, Colvin MM et al (2022) 2022 AHA/ACC/HFSA guideline for the management of heart failure: a report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines

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