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Selective and membrane-permeable small molecule inhibitors of nicotinamide N-methyltransferase reverse diet-induced obesity in mice. Nature Medicine, 25(11), 17611771

An ultrahigh dose of methylcobalamin safely and effectively slowed the progression of functional decline in patients with early-stage amyotrophic lateral sclerosis (ALS) with a moderate progression rate, according to study findings published in JAMA Neurology

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Suicidal behavior and ideation have been reported in clinical trials with other incretin mimetics indicated for weight management