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To study the ability to generate reactive oxygen species (ROS), PNT PSs were irradiated by mild sunlight (12 mW cm 2 ) emitted from a sunlight simulator, using a clinically approved PS, PpIX as the control 43

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These features greatly limit GSH accumulation

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When administered intravenously, it helps reduce oxidative stress and supports healthier skin function

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207 A recent study introduced new experiment designs using HepatoPac (Hepregen Corporation, Medford, MA, USA), spheroids or liver-on-a-chip models to assess the modulation of CYPs and transporter gene expression by peptides, but further large-scale experiments are still needed

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It has no established upper limit for toxicity at supplementation doses used in clinical practice (500 to 1,000 mcg per day)

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