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Enzymes are proteins (they require amino acids, vitamins B6 and B12, and zinc as cofactors)

May 3, 2025

Confronting Barriers Eric Topol (36:58): Yeah, no, that's a very important point

Therefore, individualized risk assessment, symptom-based monitoring, and thoughtful patient counseling are essential

It is thought that in PCOS, there is upregulation of epimerase the enzyme that converts myo-inositol to di-chiro-inositol

What keeps it directional rather than definitive: different sample sizes (263 vs 338), different dose ranges and escalation schedules, different baseline characteristics, and different statistical estimands and missing-data conventions