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when it is inhibited, neurons quickly restore glutamate neurotransmission by an ill-defined endogenous mechanism, suggesting that neurons might be making use of a storage buffer of glutamate (15)

J Struct Biol 148:226235 Morillas M, Gmez-Puertas P, Roca R, Serra D, Asins G, Valencia A, Hegardt FG (2001) Structural model of the catalytic core of carnitine palmitoyltransferase I and carnitine octanoyltransferase (COT): mutation of CPT I histidine 473 and alanine 381 and COT alanine 238 impairs the catalytic activity

Considering the large variety of therapies available, each with different attributes and mechanisms of action, along with the heterogenous nature of T2DM, the treatment landscape is understandably complicated

I go through common side effects in detail before anyone leaves my office

Due to the heterogeneity in the clinical presentation of PCOS, two well-validated murine models of PCOS 37,46,70 were used

For women with PCOS and obesity, losing some excess body weight can be beneficial