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View study Cerovecki T, Bojanic I, Brcic L, et al

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If your GIP receptors have desensitized alongside your GLP-1 receptors, switching to a pure GLP-1 agonist removes the GIP stimulus entirely, allowing those receptors to recover while you maintain GLP-1 mediated appetite suppression with a different agonist profile

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The weight loss data is similar: For weight loss specifically, there is no meaningful clinical difference

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