The honest answer is probably yes, with the right oversight, the right titration, and a plan that doesn't assume the drug does all the work
Some people choose this route because they believe the combination can offer enhanced benefits
Digestive conditions like Crohn's disease and celiac disease create similar absorption problems
(PubMed) Zhang M, Robitaille L, Eintracht S, Hoffer LJ
The Food and Drug Administration hasn't reviewed whether it is safe and effective, which is the legal path for prescription drugs to come to market
Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD et al (2021) The PRISMA 2020 statement: an updated guideline for reporting systematic reviews