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10.1097/00003086-199305000-00038 59 KawakamiT.KawaiT.TakeiN.KiseT.EdaS.UristM
Its absorption is dose-responsive and subject to saturation (Tucker et al., 1981
While the science is still evolving, doctors are cautiously optimistic
Data on the effect of SGLT2 inhibitors on muscle strength in humans are lacking, but there is at least one trial underway testing the impact of SGLT2 inhibitors (empagliflozin 10 mg once daily versus placebo for 52 weeks) on both fat free mass (measured by bioimpedance) and muscle strength (handgrip strength and five times sit to stand test) in older patients with T2DM [161]
Exclusion of trials with 60 years: HR = 0.75 (95% CI: 0.600.92)
GLP-1 therapies are showing up in ophthalmic practice whether clinicians are ready for them or not, and the evidence on their ocular effects is as mixed as the patients taking them
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