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TDP-43 triggers mitochondrial DNA release via mPTP to activate cGAS/STING in ALS

Deficiency in B12 can result in symptoms such as trouble concentrating, memory problems, and mood changes

stacking Dihexa with cholinergic enhancers is theoretically appealing: Examples: Alpha-GPC, CDP-choline, or acetylcholinesterase inhibitors (ACh-E inhibitors) Rationale: Dihexa enhances synaptic plasticity

For this reason, peptides are often considered more effective for stimulating endogenous collagen synthesis, rather than simply supplying collagen externally

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