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Ralston may increase the dose if the patients body forms a tolerance to the drug
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14 These modifications should be discussed before initiating obesity management medications and reinforced throughout treatment
Additionally, baseline metabolic health, insulin sensitivity, stomach motility, and concurrent medications affect efficacy and tolerability
Source: STEP 1 trial data (Wilding et al., NEJM 2021) Tip: If side effects are severe at a new dose, your prescriber may hold the current level for an extra 4 weeks or drop back to the previous dose temporarily
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