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Were going direct with the ad so that we can change that conversation and help our customers not only understand more fully the challenges facing them, but also to advocate for them and give them the opportunity to access the care that they need. Hims & Hers hopes its push for new patients will outlive the 15 minutes of fame characteristic of Super Bowl commercials

A 2021 review published in Biomedicine & Pharmacotherapy explains that silymarin, the main active compound in milk thistle, can:25 Regulate the cell cycle, helping to ensure proper division and replication Induce apoptosis, or programmed cell death, by which the body can eliminate mutated cells (e.g., cancer cells) Regulate the body's immune response, increasing its ability to recognize and attack cancer cells Keep tumor cells from growing and spreading Inhibit angiogenesis, the process by which tumors create new blood vessels that increase their blood supply and help them grow The review specifically discusses silymarin's therapeutic potential for gastrointestinal cancer, but as another set of researchers note, silymarin has a pleiotropic effect, meaning it can act on multiple targets.26 Again, more research may be needed, but the current science suggests that milk thistle may have fairly broad complementary utility in cancer therapy

PubMed PMID: 16685128

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Side effects Commonly reported side effects include: Nausea Constipation Diarrhea Vomiting Stomach (abdominal) pain Indigestion Headache Other potential side effects: Fatigue Belching Heartburn Bloating Hair loss Decreased appetite Gastroesophageal reflux disease Injection site reactions Most GI side effects are more common in the first few weeks and tend to ease as your body adjusts