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10.1016/j.tibs.2017.11.004 261 SolimanH

Pharmaceutical GLP-1 medications have been tested in randomized, double-blind, placebo-controlled trials involving thousands of participants

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Clinical encounters, prescriptions, and diagnoses were required to occur between January 1, 2021, and April 2024, a period selected to capture contemporary use of semaglutide following its U.S

However, obesity represents chronic medical condition influenced by genetics, metabolism, and environment not just willpower failure meaning some patients benefit from long-term medication therapy just as diabetics need ongoing insulin or hypertensive patients require continued blood pressure medications