51 The lung is particularly at risk from oxidative damage as it is exposed to oxygen, oxygen radicals produced by alveolar macrophages, inhaled environmental and blood-borne toxins, including cigarette smoke and atmo-spheric pollutants
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Recent studies have shown that C16-carnitine induces mitochondrial dysfunction and leads to calcium overload by increasing mitochondrial fission in SH-SY5Y cells
197,198,199,200 Mast cells also play an important role in allergy by releasing histamine and other mediators after activation by IgE-allergen complexes that bind to FcRI on these cells
Ellison M et al (2016): Prolonged Paralysis Following Emergent Cesarean Section with Succinylcholine Despite Normal Dibucaine Number