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Dosing typically begins at a lower dose, suggested initiation of 20 units (0.2 mL) weekly for the first 4 weeks, then escalates according to a titration schedule: Weeks 14: Inject 20 units (0.2 mL) one time per week Weeks 58: Inject 40 units (0.4 mL) one time per week Weeks 912: Inject 70 units (0.7 mL) one time per week Weeks 1316: Inject 90 units (0.9 mL) one time per week Weeks 1720: Inject 120 units (1.2 mL) one time per week Week 21+: Inject 140 units (1.4 mL) one time per week Dosing may deviate from this pattern to accommodate patient-specific needs
Your body does not make it
That is why many prenatal vitamins are fortified with folate
"Effects of folate and vitamin B12 on cognitive function in adults and the elderly"
That distinction is still being actively refined, which is part of what makes it an interesting subject for independent research
Because the needle stays in the fatty layer, there is less chance of catching a nerve or a blood vessel than with a deeper injection, which is one reason some clinicians prefer it for maintenance dosing
