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This divergent evidence may be due to the different experimental conditions of the studies
The study published in JAMA Psychiatry found that patients with alcohol use disorder (AUD) who were prescribed GLP-1 drugs, popularly known by their brand names Ozempic and Wegovy, had a significantly lower risk of hospitalization for alcohol-related issues
Ozempic slows gastric emptying and affects gut motility, which could theoretically influence bowel function in diverticular disease
Leptin normally increases energy expenditure and reduces food intake
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These drugs were classified as antidiabetic (9/36), antineoplastic (8/36), immunomodulatory (3/36), anti-hypertensive (2/36), antiatherosclerotic (2/36), antipsychotic (2/36), antibacterial (2/36), diuretic (1/36), antiepileptic (1/36), gastric acid secretion inhibitor (1/36), antiviral (1/36), and other drugs (4/36) (Supplementary Table S3)
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