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For this reason, synthetic analogs of neurosteroids, which are more resistant to metabolism and better able to cross the BBB, are under investigation for use as anxiolytics, antidepressants, cognitive enhancers, anesthetics, and anticonvulsants (132, 388, 389)
[ 1 ] The pineal gland is a small organ located near the center of the brain
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The social environment further plays a critical role in supporting behavioral change
Free Radical Biology and Medicine, 19(2), 227-250
These transdermal products face similar evidence limitations as oral supplements, with the added concern that berberine delivery through the skin has not been well studied
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