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Notably, patients with mutations in GGT1 often present with developmental disorders, accumulation of GSH (glutathionaemia and glutathionuria) and reduced circulating levels of cystine 25

Notably, the main features of the model outputs are robust to changes in the values of the different parameters

source: synthetic

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Nat Rev Genet 23(6):355368 Morrell ED, Radella F 2nd, Manicone AM, Mikacenic C, Stapleton RD, Gharib SA et al (2018) Peripheral and alveolar cell transcriptional programs are distinct in acute respiratory distress syndrome