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Variables de estudio Variables universales y clnicas Al momento de la inclusin, para cada paciente se recogieron datos demogrficos y clnicos: edad, sexo, diagnstico, gravedad valorada por APACHE II (Actue Physiology and Chronic Health Evaluation II) 17 y curso clnico mediante el clculo del SOFA (Sepsis-Related Organ Failure Assesment) 18

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3 BMI 18.5-24.9: HR 0.61 (95% CI 0.42-0.89) BMI 25-29.9: HR 0.82 (95% CI 0.66-1.03) BMI 30-34.9: HR 0.77 (95% CI 0.63-0.94) BMI 35-39.9: HR 0.60 (95% CI 0.47-0.77) BMI 40: HR 0.74 (95% CI 0.60-0.91) 3 A limitation of the study was changes in patients' weight was not captured so it could not determine the impact of weight loss and VTE incidence

Thus, changes in these biomarkers do not accurately assess real-time brain function since the underlying and established deficits in neuronal functioning are unaffected by their absence

For people wondering about the timing aspects of their protocol, the best time of day to take semaglutide has no bearing whatsoever on drug test outcomes, since detection is simply not a function of timing or concentration