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Targeting ferroptosis for cancer therapy: Exploring novel strategies from its mechanisms and role in cancers
J Comp Neurol 373:157172 Lubos E, Loscalzo J, Handy DE (2011) Glutathione peroxidase-1 in health and disease: from molecular mechanisms to therapeutic opportunities
Specifically, the pcDNA3.1-GST DAF -ATP6AP1L transfection resulted in an ATP6AP1L gene expression level of 47 times that of the control, and the affinity cell sorting procedure significantly elevated the apparent expression level in the enriched cells by 253 times that of the control
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Its efficacy involves the competitive exclusion of pathogens and direct antagonism of multidrug-resistant organisms, clinically correlating with reduced durations of diarrheal diseases and enterocolitis (62, 63)
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