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A novel anti-CD40 monoclonal antibody, iscalimab, for control of Graves hyperthyroidism: a proof-of-concept trial

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For appropriate candidates, under proper clinical oversight, this class represents one of the more studied areas of peptide application

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Another strategy to alleviate disease-causing effects of autoreactive IgG is to block activating FcRs, thereby preventing pathological IgG-mediated activation of FcR-expressing immune cells