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The April 2024 paper and a comprehensive 2023 Pharmaceuticals review (PMC10224484) detail how peripheral BPC-157 administration produces corresponding central nervous system effects through multiple mechanisms

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Selective serotonin reuptake inhibitors (SSRIs) increase brain levels of ALLO in humans and animals, suggesting that the anxiolytic effects of SSRIs may be related in part to their effect on CNS levels of this endogenous GABAergic modulator (93, 297301)

These track inflammation and general health, not FOXO4-DRI activity directly

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