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IDH1/2 mutants use NADPH to transform -ketoglutarate (-KG) into D-2-hydroxyglutarate (D-2HG) which can act as an oncometabolite
Azmi S, et al
If we have an idea that can both work in diabetes in a much safer way than in insulin, and then also at the same time work in obesity
Wegovy (semaglutide 2.4 mg) is a once-weekly GLP-1 receptor agonist licensed by the MHRA for chronic weight management in adults with obesity or overweight with comorbidities
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